Age and immunosuppression status affects vaccine effectiveness in kidney patients

February 20, 2024

The CONVINCE study: Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure

Do two different kinds of hemodialysis produce different outcomes in adult populations with kidney failure? The investigators examined deaths from any cause as outcomes of primary interest. “Outcome” refers to an event over time that is measured to monitor the impact of a treatment in a given population. The investigators were also interested in looking at death from heart and blood vessel diseases, and recurrent hospitalizations.

The two kinds of hemodialysis treatments were high flux hemodialysis (HD) and high dose hemodiafiltration (HDF), which use different methods to move substances across the dialysis filters to clean the blood.

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Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure

Blankestijn PJ, Vernooij RWM, Hockham C, Strippoli GFM, Canaud B, Hegbrant J, Barth C, Covic A, Cromm K, Cucui A, Davenport A, Rose M, Török M, Woodward M, Bots ML; CONVINCE Scientific Committee Investigators

New England Journal of Medicine